Research Article
Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis
Figure 2
Inhibition of synovial macrophage pyroptosis may alleviate synovitis in KOA rats. (a) Representative synovial tissues of each group stained with HE staining (200×). Arrow: inflammatory cell infiltration. (b) Protein expressions of IL-1β, IL-18, and HMGB1 between groups. , in comparison with the Normal group. #, in comparison with the KOA group (). (c) Typical protein bands for each group. (d) mRNA levels of IL-1β, IL-18, and HMGB1 between groups. The trend is consistent with protein expression.
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