Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation

Figure 2

Plasma PTX3 and senescent-associated inflammatory cytokine concentrations. Plasma PTX3 concentrations were significantly lower in middle-aged compared to young adults (a). In addition, no differences in the proinflammatory cytokine IL-6 were observed (b), whereas plasma TNF-α concentrations were greater in middle-aged compared to young adults (c). Likewise, no differences in the anti-inflammatory cytokine IL-10 were observed (d), whereas plasma TGF-β concentrations were lower in middle-aged compared to young adults (e). indicates a significant difference in middle-aged compared to young adults ().

(a)

(b)

(c)

(d)

(e)