Research Article

Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators

Figure 5

Decision tree for classifying patients into different categories or severities of appendicitis based on concentrations of 4 informative cytokines. Thresholds presented are blood concentrations of the cytokines. Concentrations are in ng/mL for PCT, mg/L for CRP and SAA, and pg/mL for all others. Numbers in the category below refer to how many individuals in each terminal node have been classified into each category: green = no appendicitis; orange = appendicitis; red = severe appendicitis; and blue = nonappendicitis sepsis.