Cytokines and Chemokines in Pediatric Appendicitis: A Multiplex Analysis of Inflammatory Protein Mediators

Table 3

Operating characteristics (95% confidence interval) of patient categorization based on the decision tree.

Patient category	Sensitivity	Specificity	PPV	NPV
Nonappendicitis abdominal pain	0.916 (0.834-0.965)	0.843 (0.758-0.908)	0.826 (0.733-0.897)	0.925 (0.851-0.969)
Simple appendicitis	0.646 (0.495-0.778)	0.920 (0.862-0.960)	0.738 (0.580-0.861)	0.882 (0.818-0.930)
Severe appendicitis	0.581 (0.391-0.755)	0.968 (0.926-0.989)	0.783 (0.563-0.925)	0.920 (0.867-0.957)
Nonappendicitis sepsis	0.826 (0.612-0.950)	0.945 (0.898-0.974)	0.679 (0.476-0.841)	0.975 (0.936-0.993)
Nonappendicitis abdominal pain	0.916 (0.834-0.965)	0.860 (0.776-0.921)	0.844 (0.753-0.912)	0.925 (0.851-0.969)
Appendicitis	0.722 (0.609-0.817)	0.925 (0.857-0.967)	0.877 (0.772-0.945)	0.817 (0.736-0.881)
Nonappendicitis sepsis	0.826 (0.612-0.950)	0.944 (0.897-0.974)	0.679 (0.476-0.841)	0.975 (0.936-0.993)