Mycobacterium tuberculosis Requires Cholesterol Oxidase to Disrupt TLR2 Signalling in Human Macrophages

Figure 3

TRAF6 protein level in Mtb-infected macrophages. The macrophages were infected with (a) wild-type, (b) ΔchoD, or (c) ΔchoD-choD strains for 0.5 to 24 hours. The TRAF6 protein level was assessed using the immunoblot-ECL method. Representative immunoblots of the TRAF6 protein level are shown. The bands were quantified by densitometric analysis. The data are presented as the from 5 independent experiments. Macrophages infected with the wild-type or ΔchoD-choD vs. noninfected macrophages, (Wilcoxon’s signed rank test).

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