Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo

Figure 1

In vitro expression of the Mas receptor in M0, M(LPS+IFN-γ), and M(IL-4) macrophages. (a) Representative images of the Mas receptor detection by immunofluorescence (orange) and nuclei by DAPI (blue). (b) Quantification of fluorescence intensity and (c) relative mRNA expression for the Mas receptor normalized by the M0 group in M(LPS+IFN-γ) and M(IL-4) phenotypes. Results were obtained by one-way ANOVA (1b) or by the nonparametric Kruskal-Wallis test (1c) and are expressed as the mean ± SEM of and independent experiments for protein and mRNA, respectively.

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