Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus

Figure 1

Percentage of B and T lymphocytes with bound platelets in HD and SLE patients. (a) A representative image of B lymphocytes (CD19+), CD4+ T lymphocytes (CD19-, CD4+, and CD5+) and CD8+ T lymphocytes (CD19-, CD4-, and CD5+) with bound platelets (PLTs) in HD and SLE patients is shown. (b) The dot plot shows the percentage of B and CD4 and CD8 T lymphocytes with bound platelets in HD () and SLE patients (). CD4 and CD8 T lymphocytes had more bound platelets than B lymphocytes in SLE patients (both ), but not in HD. Data are presented as the mean. Statistical analysis was performed using the -test for comparison between HD and SLE and paired -test for the subpopulation comparisons in HD and SLE. and .

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