Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus

Figure 5

Percentage of lymphocytes with bound platelets in SLE patients according to clinical features. Whole blood from SLE patients () was incubated with anti-CD4-PECy7, CD5-PE, CD19-PEDy647, and CD41a-FITC mAbs for flow cytometry analysis. Dot plots of percentages of CD19+ B lymphocytes and CD4+ and CD8+ T lymphocytes with bound platelets in SLE patients segregated according to (a) positive or negative anti-dsDNA, (b) positive or negative hematuria, (c) <85 or 85-193 mg/dl of C3, and (d) >2.5 or ≤2.5 mg/mmol of albumin/creatinine are shown. Data are presented as the mean. Statistical analysis was performed using the Mann-Whitney test. , , and .

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