Research Article
Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus
Table 1
Demographic, clinical, and laboratory characteristic data of study patients.
| | SLE patients | HD |
| General conditions | | | Age; year, | | | Gender (%) () women | 100 (21) | 75 (12) | Years of evolution, | | | SLEDAI; mean (range) | 2.62 (0-12) | | Laboratory parameters | | | ESRa (mm/h, ) | | | CRPb (mg/l, ) | | | Complement C3 (mg/dl, ) | | | Complement C4 (mg/dl, ) | | | Decreased C3 or C4 (%) () | 80.95 (17) | | Anti-dsDNA (U/ml), mean (range) | 74.8 (22-300) | | Positive anti-dsDNA (%) () | 42.8 (9) | | Positive ANA (%) () | 95.23 (20) | | Positive anti-Sm (%) () | 4.7 (1) | | Positive antiphospholipid antibody (%) () | 14.28 (3) | | Leukopenia and/or lymphopenia (%) () | 14.28 (3) | | Clinical features | | | Renal involvement (%) () | 23.8 (5) | | Hematuria | 23.8 (5) | | | 23.8 (5) | | Cutaneous involvement (%) () | 28.57 (6) | | Oral or nasal ulcers | 4.7 (1) | | Alopecia | 4.7 (1) | | Photosensitivity | 23.8 (5) | | Butterfly erythema | 9.5 (2) | | Arthritis (%) () | 19.1 (4) | | Nervous system disorder | 4.7 (1) | | Treatment (%) () | | | None | 9 (2) | | Mycophenolate | 14 (3) | | Prednisone | 48 (10) | | Hydroxychloroquine | 62 (13) | | Azathioprine | 24 (5) | | Tacrolimus | 9 (2) | | NSAIDc | 14.28 (3) | | Aspirin | 23.8 (5) | |
|
|
aESR: erythrocyte sedimentation rate. bCRP: C-reactive protein. cNSAID: nonstereoidal anti-inflammatory drugs.
|