Research Article

Association of Platelet Binding to Lymphocytes with B Cell Abnormalities and Clinical Manifestations in Systemic Lupus Erythematosus

Table 1

Demographic, clinical, and laboratory characteristic data of study patients.

SLE patientsHD

General conditions
 Age; year,
 Gender (%) () women100 (21)75 (12)
 Years of evolution,
 SLEDAI; mean (range)2.62 (0-12)
Laboratory parameters
 ESRa (mm/h, )
 CRPb (mg/l, )
 Complement C3 (mg/dl, )
 Complement C4 (mg/dl, )
 Decreased C3 or C4 (%) ()80.95 (17)
 Anti-dsDNA (U/ml), mean (range)74.8 (22-300)
 Positive anti-dsDNA (%) ()42.8 (9)
 Positive ANA (%) ()95.23 (20)
 Positive anti-Sm (%) ()4.7 (1)
 Positive antiphospholipid antibody (%) ()14.28 (3)
 Leukopenia and/or lymphopenia (%) ()14.28 (3)
Clinical features
 Renal involvement (%) ()23.8 (5)
  Hematuria23.8 (5)
  23.8 (5)
 Cutaneous involvement (%) ()28.57 (6)
  Oral or nasal ulcers4.7 (1)
  Alopecia4.7 (1)
  Photosensitivity23.8 (5)
  Butterfly erythema9.5 (2)
 Arthritis (%) ()19.1 (4)
 Nervous system disorder4.7 (1)
Treatment (%) ()
 None9 (2)
 Mycophenolate14 (3)
 Prednisone48 (10)
 Hydroxychloroquine62 (13)
 Azathioprine24 (5)
 Tacrolimus9 (2)
 NSAIDc14.28 (3)
 Aspirin23.8 (5)

aESR: erythrocyte sedimentation rate. bCRP: C-reactive protein. cNSAID: nonstereoidal anti-inflammatory drugs.