Research Article
METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway
Figure 3
LPS promoted the expression and activity of METTL3 in pTHP-1 cells. (a) Increased mRNA level of METTL3 in cells (; LPS stimulation for 0 hr, 6 hrs, 12 hrs, and 24 hrs; and ). (b) Increased expression of METTL3 protein in cells (; LPS stimulation for 0 hr, 6 hrs, 12 hrs, and 24 hrs). (c) Total m6A content in cells (LPS stimulation for 0 hr, 6 hrs, 12 hrs, and 24 hrs; ; and ).
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