CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Primary antibody</td><td class="align_center">Secondary antibody</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Rabbit anti-nephrin pAb (Abcam)</td><td class="align_center">IRDye 800 conjugated goat anti- rabbit IgG antibody (LI-COR)</td></tr><tr><td class="align_left">Rabbit anti-podocin pAb (Sigma)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-desmin pAb (Abcam)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-ADRP pAb (Abcam)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-CD36 pAb (Abcam)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-SREBP-1 pAb (Santa Cruz)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-PPAR<i>α</i> pAb (Santa Cruz)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-NLRP3 pAb (Novus)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-caspase1 P10 pAb (Santa Cruz)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Rabbit anti-IL-1<i>β</i> pAb (Abcam)</td><td class="align_center">Ditto</td></tr><tr><td class="align_left">Mouse anti-<i>β</i>-actin mAb (Sigma)</td><td class="align_center">IRDye 700 conjugated goat anti-mouse IgG antibody (LI-COR)</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Primary and secondary antibodies for Western blot assays.</div>

Mediators of Inflammation

tab2

Table 2

Table 2: CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy 