Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality

Table 4

Multiple linear regression model of prediction of each inflammatory biomarker under study, considering all other evaluated biomarkers, and NT-proBNP and TIMP-1, considering all inflammatory markers in end-stage renal disease patients.

Dependent variable	Model	Unstandardized coefficients		Standardized coefficients
			Std. error	Beta
PTX3	(Constant)	1.721	0.382		4.504	<0.001
	NT-proBNP	0.008	0.002	0.244	3.960	<0.001
	oxLDL/LDL-C ratio	-14.772	4.327	-0.202	-3.414	<0.001
	TIMP-1	0.001	0.000	0.173	2.787	0.006
hsCRP	(Constant)	-0.117	0.324		-0.361	0.718
	IL-6	0.071	0.007	0.547	10.505	<0.001
	HDL-C	-0.011	0.004	-0.137	-2.718	0.007
	LDL-C	0.005	0.002	0.127	2.543	0.012
	TIMP-1	0.001	0.000	0.127	2.462	0.015
IL-6	(Constant)	3.206	0.532		6.023	<0.001
	hsCRP	4.588	0.394	0.600	11.657	<0.001
TNF-α	(Constant)	3.516	0.171		20.592	<0.001
	IL-6	0.069	0.016	0.271	4.383	<0.001
NT-proBNP	(Constant)	-1.079	4.232		-0.255	0.799
	PTX3	9.041	1.950	0.282	4.635	<0.001
	IL-6	0.882	0.275	0.195	3.209	0.002
TIMP-1	(Constant)	491.588	18.095		27.167	<0.001
	PTX3	32.583	8.419	0.237	3.870	<0.001
	hsCRP	32.720	9.074	0.221	3.606	<0.001

PTX3: pentraxin 3; NT-proBNP: N-terminal-pro-B-type natriuretic peptide; oxLDL/LDL-C: oxidized low-density lipoprotein/low-density lipoprotein cholesterol; TIMP-1: tissue inhibitor of metalloproteinase-1; hsCRP: high-sensitivity C-reactive protein; IL-6: interleukin-6; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TNF-α: tumor necrosis factor-α.