Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages

<div>Principal component analysis. The protein spots on gels of nuclear proteins from M1, M2, and control macrophages were analyzed by PCA. (a) Protein abundance, where PC1 accounts for 52.9% of the spot variability within the gels and PC2 40.2%; (b) SNO, PC1 53.1% and PC2 40.5%; and (c) phosphorylation, PC1 42.1% and PC2 30.8%. These values confirm the impact of the M<i>φ</i> polarization on the protein abundance, SNO, and phosphorylation states.</div>

Mediators of Inflammation

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Figure 4

Figure 4: Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages 