Research Article

The Influence of Inflammation on Fibrinogen Turnover and Redistribution of the Hemostatic Balance to a Prothrombotic State in High On-Treatment Platelet Reactivity-Dual Poor Responder (HTPR-DPR) Patients

Table 1

Characteristics of the study group.

CLIAMI value

Age (yrs)NS
Male sex, (%)21 (91.3)19 (88.4)NS
BMI (kg/m2)NS
INR (r.v. 0.8-1.2)NS
Index APTT (r.v. 0.84-1.16)NS
Fibrinogen (g/L) (r.v. 1.5-4.5)NS
Platelets (×109/L) (r.v. 150-450)NS
Platelet distribution width (%) (r.v. 8.0-18.0)NS
Mean platelet volume (fL) (r.v. 8.0-12.0)NS
White blood cells (×109/L) (r.v. 4.5-10.0)NS
Red blood cells (×1012/L) (r.v. 4.5-5.5)NS
Hemoglobin (g/dL) (r.v. 13.0-18.0)NS
Hematocrit (%) (r.v. 40-54)NS
hs-CRP (mg/L) (r.v. <5.0)<0.006
Thrombomodulin (μg/L) (r.v. 1.8-4.4)NS
von Willebrand antigen (U/mL) (r.v. 0.51-7.71)NS
von Willebrand activity (%) (r.v. 55-140)<0.01
Prothrombin fragment F1+2 (nmol/L) (r.v. 0.2-2.78)<0.01
Tissue factor (μg/L) (r.v. 28-255)NS

Abbreviations: CLI: critical limb ischemia; AMI: acute myocardial infarction; BMI: body mass index; hs-CRP: high-sensitivity C-reactive protein.