Research Article
Anti-TNF-α Monoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease
Table 1
The clinical characteristics of IBD patients and healthy volunteers.
| | HC | UC (A/R)b | CD (A/R)b |
| Patients | 22 | 22/11 | 25/41 | Age, years (range) | (15-67) | (12-79) | (11-89) | Gender (M/F) | 13/9 | 18/15 | 34/32 | Medical therapy received | | | | 5-ASA | | 19 | 40 | Immunosuppressants | | 14 | 26 | Biologics | | 0 | 0 | Disease extenta | | | | Proctosigmoiditis (E1) | | 10 | | Left-sided colitis (E2) | | 9 | | Extensive colitis (E3) | | 14 | | Disease locationa | | | | Ileum only (L1) | | | 21 | Colon only (L2) | | | 18 | Ileum and colon (L3) | | | 16 | Upper gastrointestinal tract (L4a) | | | 11 |
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aMontreal classification; bA/R: active/remission.
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