Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats

<div>Variations of PWT (a) and PWL (b) during the progression of STZ-induced diabetes (Dia) in rats. PWT and PWL were significantly decreased from 1 week to 5 weeks as detected by electronic Von Frey and Hargreaves test. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats 

Figure 2 | Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats 