Curcumin Attenuates Asthmatic Airway Inflammation and Mucus Hypersecretion Involving a PPARγ-Dependent NF-κB Signaling Pathway In Vivo and In Vitro
PPARγ expression was inhibited after shRNA-PPARγ transfection in BEAS-2B cells. BEAS-2B cells were transfected with shRNA-PPARγ or shRNA-scrambled. Twenty-four hours after transfection, PPARγ expression was analyzed. (a) qPCR was performed to measure PPARγ mRNA expression. (b) Western blotting was obtained to evaluate PPARγ protein expression. Quantitative data were presented as (). compared with control. compared with IL-4. compared with IL-4 + Cur + shRNA-PPARγ.