Differences in cNOS/iNOS Activity during Resistance to Trypanosoma cruzi Infection in 5-Lipoxygenase Knockout Mice

Figure 8

Plasmatic antioxidant profile. (a) Wild-type (129 WT mice) and (b) 5-LO^-/- mice. Mice were infected with trypomastigote forms of T. cruzi (Y strain) and were treated or untreated with NOS inhibitors. AG: infected mice treated with aminoguanidine (50 mg/kg/day i.p.); LN: infected mice treated with L-NAME (LN; 20 mg/kg/day i.p.); AG+LN: infected mice treated with aminoguanidine (50 mg/kg/day i.p. plus L-NAME 20 mg/kg/day). Uninfected mice were used as controls. animals in each group. Values represent the and are representative of two independent experiments .

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