Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study

Figure 6

Quantification of histological findings—therapeutic. Histopathologic scores of synovial inflammation (a), chondrocyte death (b), cartilage erosion (c), bone erosion (d), and proteoglycan depletion (e) in PBS and RvE1. The parameters showed normal distribution, and therefore, Student’s -test was used to assess the differences between the groups. No differences were found when RvE1 was used for the treatment of CIA mice.

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