Escherichia coli Nissle 1917 Protects Intestinal Barrier Function by Inhibiting NF-κB-Mediated Activation of the MLCK-P-MLC Signaling Pathway

Figure 1

The effect of EcN on mice with sepsis induced by CLP operation. (a) Food and water consumptions during the 14 days of oral gavage with saline or EcN (). (b) The weight of mice after 14 days of oral gavage with saline or EcN (). (c) FD-4 flux at 24 h after sham operation or CLP operation. (d) The mucosal cells of a mouse intestine were collected at 24 h after sham operation or CLP operation, and the total proteins were harvested followed by western blotting assays. Results were expressed as the (). vs. the sham group. ^# vs. the CLP group.

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