Dynamic Changes of Th1 Cytokines and the Clinical Significance of the IFN-γ/TNF-α Ratio in Acute Brucellosis

Figure 2

(a) The correlation analyses between IFN-γ and TNF-α levels and the clinical parameters of patients with acute brucellosis (). The correlation analysis charts showed no statistically significant differences () and negative correlations between IFN-γ levels and several clinical parameters, including (A) erythrocyte sedimentation rate (ESR), (B) C-reactive protein (CRP), (C) thrombocyte (PLT), (D) white blood cell (WBC), (E) aspartate aminotransferase (AST), and (F) alanine aminotransferase (ALT). (b) No correlations were detected between TNF-α levels and the clinical parameters. Negative correlations were detected between TNF-α levels and the clinical indicators, including (A) ESR, (B) CRP, (C) PLT, (D) WBC, (E) AST, and (F) ALT. Abbreviations: IFN-γ: gamma-interferon; TNF-α: tumor necrosis factor-alpha; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; PLT: thrombocyte; WBC: white blood cell (leukocyte); AST: aspartate aminotransferase; ALT: alanine aminotransferase.

(a)

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