Electronegative LDL from Rabbits Fed with Atherogenic Diet Is Highly Proinflammatory

Figure 1

Characterization of LDL(-) in rabbit plasma. Rabbits were fed an atherogenic diet for 6 weeks, then LDL was isolated by ultracentrifugation and loaded onto a UnoQ6 column to separate native (n)LDL and electronegative LDL (LDL(-)). (a) Representative fast protein liquid chromatographic analysis showing the distribution of the nLDL and LDL(-). (b) Isolated nLDL and LDL(-) were analyzed by agarose gel electrophoresis.

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(b)