Research Article
Electronegative LDL from Rabbits Fed with Atherogenic Diet Is Highly Proinflammatory
Figure 5
Effects of copper oxidation of nLDL and LDL(-) on IL-1β, IL-6, and TNF-α production in THP-1 macrophages. THP-1 macrophages were treated with 20 μg/ml of nLDL, LDL(-), Cu-ox-nLDL, or Cu-ox-LDL(-) for 24 h, then levels of IL-1β (a), IL-6 (b), and TNF-α (c) in the medium were measured by ELISA. Values are the of three independent experiments. , compared to LDL(-)-treated cells.
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