Circulating ANGPTL8 Is Associated with the Presence of Metabolic Syndrome and Insulin Resistance in Polycystic Ovary Syndrome Young Women

Table 4

Association of circulating ANGPTL8 with MetS in fully adjusted models.

Model adjust	MetS			Insulin resistance
	OR	95% CI		OR	95% CI
Age	6.69	3.90-11.47	<0.001	4.82	3.17-7.32	<0.001
Age, BMI	4.79	2.74-8.36	<0.001	3.19	2.07-4.93	<0.001
Age, BMI, WHR	4.47	2.49-8.03	<0.001	3.27	2.11-5.08	<0.001
Age, BMI, WHR, HbA1c	4.51	2.49-8.17	<0.001	3.24	2.06-5.12	<0.001
Age, BMI, WHR, HbA1c, FIns	3.95	2.15-7.26	<0.001	2.19	1.29-3.71	<0.01
Age, BMI, WHR, HbA1c, FIns, lipid profile	4.12	2.16-7.87	<0.001	2.49	1.42-4.36	<0.01
Age, BMI, WHR, HbA1c, FIns, lipid profile, hormone	5.71	2.51-13.0	<0.001	2.43	1.29-4.61	<0.01

Results of binary logistic regression analysis are presented as the odds ratio (OR) of being in MetS status decrease in circulating. BMI: body mass index; WHR: waist-to-hip ratio; FAT (%): the percentage of fat in vivo; SBP: systolic blood pressure; DBP: diastolic blood pressure; lipid profile: including total cholesterol, FFA, triglyceride, and LDL- and HDL-cholesterol. Hormone: including SHBG, DHEAS, E2, TEST, LH, FSH, PRL, and PROG.