Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation

Figure 6

Rg1 treatment relieved ER stress in CLP mice. (a) Representative images for IER1α and CHOP proteins in lung tissue extracts from CLP mice by Western blotting. (b) Quantification of IER1α and CHOP protein levels. (c) Representative images ATF6 and GRP78 proteins by Western blotting. (d) Quantification of relative expression of ATF6 and GRP78. (e) Representative images for SIRT1 protein expression by Western blotting. (f) Quantification of relative expression of SIRT1. ; , compared to the sham or CLP model group. Data were shown as mean + SD based on three independent experiments.

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