Research Article

Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: A Comparative Study

Table 4

The effect of high-salt intake on the frequencies of cells expressing CD11b/c, CD11a, and CD49d on peripheral blood leukocyte subpopulations of Sprague-Dawley rats.

Peripheral blood leukocytesLS dietHS diet

Granulocytes % parent0.004
 CD11b/c+ granulocytes % parent1.000
 CD11a+ granulocytes % parent0.858
 CD49d granulocytes % parent0.111
Monocytes % parent0.553
 Non-CD3 mononuclear cells % parent0.039
 CD11b/c+ monocytes % parent0.438
 CD11a total monocytes % parent0.209
 CD11ahigh monocytes % parent0.015
 CD49d total monocytes % parent0.025
 CD49dhigh monocytes % parent0.001
 CD49ddim monocytes % parent0.004
Lymphocytes % parent0.002
CD3+ lymphocytes % parent0.434
 CD11b/c+CD3+ lymphocytes % parent0.077
 CD11b/c+ B cells % parent0.064
 CD11a+CD3+ T cells % parent0.132
 CD11a+ cytotoxic lymphocytes % parent100.00100.001.000
 CD11a+ helper % parent100.00100.001.000
 CD49d+CD3+ lymphocytes % parent0.034
 CD49d+CD3+ high lymphocytes % parent0.011
 CD49d+ cytotoxic lymphocytes % parent0.071
 CD49d+ T helper % parent0.137
 CD49d+ B cells % parent0.008

LS: low-salt diet; HS: high-salt diet; per group; data was compared using -test, and was considered significant.