Association between Irisin, hs-CRP, and Metabolic Status in Children and Adolescents with Type 2 Diabetes Mellitus

Table 1

Demographic and clinical characteristics of the population.

Parameter	T2DM ()	Healthy controls ()	value
Male	10 (50)	10 (50)	1.00
Female	10 (50)	10 (50)
Age in years			<0.001
Obesity^a	14 (70)	0 (0)	<0.001
Overweight^b	4 (20)	0 (0)
Normal weight	2 (10)	20 (100)
Acanthosis nigricans	19 (95)	0 (0)	<0.001
Tanner 1-2	0 (0)	11 (55)	<0.001
Tanner 3-5	20 (100)	9 (45)

T2DM = type 2 diabetes mellitus. ^aObesity was defined as BMI ≥ 95th percentile according to CDC criteria. ^bOverweight was defined as BMI ≥ 85th percentile and <95th percentile according to CDC criteria. Data are presented as absolute number and percentage (%) unless specified otherwise.