Research Article
Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes
Figure 3
Altered apoptosis and proliferation caused by gain or loss of DICER1 function for 48 h in human synoviocytes SW982. (a) Flow cytometry results of Annexin V-FITC staining after DICER1 siRNA transfection for 48 h. (A) Representative histogram; (B) quantitative analysis of mean fluorescence intensity. (b) Flow cytometry results of Annexin V-FITC staining after DICER1 was overexpressed for 48 h. (A) Representative histogram; (B) quantitative analysis of mean fluorescence intensity. (c) Cell counting kit-8 assay for cell proliferation detection. Bar: from three independent transfection experiments, and triplicates were used for each transfection experiment. using the Mann-Whitney test.
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