NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs

Figure 3

Calhex 231 prevented the activation of NLRP3 inflammasome in VSMCs induced by Ang II. (a) Western blot images of CaSR and NLRP3 expression induced by Ang II in a time-dependent manner. (b) Quantification of the proteins from A. , , and vs. 0 h, . (c) CaSR regulated NLRP3 inflammasome activation induced by Ang II. Western blot images of CaSR, NLRP3, ASC, and caspase 1. (d–h) Quantitative analyses of the proteins from C. , , vs. control; and vs. Ang II.

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