Calprotectin and Calgranulin C as Biomarkers of Pancreatic Tumors: Baseline Levels and Level Changes after Surgery
Table 3
The comparisons of the level of AMS in the pancreatic drainage fluid; the levels of calprotectin, calgranulin C, and CRP in the serum; and the WBC count in patients with POPF grades A, B, and C and those with uncomplicated postoperative courses.
0
A
B
C
Calprotectin (ng/mL)
Day 0
2731 (1705-4781)
2681 (2289-3017)
3714 (2284-4550)
2274 (1597-3558)
Day 1
6233 (4354-8586)
6540 (5617-7630)
11065 (6808-12425)
8253 (5336-10856)
Day 3
7337 (4940-11306)
12649 (7549-19181)
18983 (15364-22685)
12087 (8930-15833)
Day 5
8118 (5671-11794)
11569 (9442-20617)
19898 (13254-23208)
14496 (11787-15597)
Day 7
9309 (5148-12605)
12735 (10835-21866)
21358 (14284-24551)
16643 (12150-19353)
Calgranulin C (ng/mL)
Day 0
42.5 (19.7-60.6)
50.8 (38.8-54.1)
60.4 (24.7-96.6)
34.3 (25.2-48.2)
Day 1
118.6 (76.8-165.1)
108.8 (97.0-146.2)
202.9 (155.5-242.7)
112.1 (97.9-155.7)
Day 3
154.6 (93.4-235.1)
254.7 (158.7-402.2)
447.3 (330.8-542.6)
279.8 (229.4-334.9)
Day 5
195.0 (114.5-259.7)
266.9 (144.2-453.8)
419.2 (294.9-647.5)
308.8 (214.3-379.3)
Day 7
191.1 (111.0-276.0)
262.6 (204.1-450.3)
448.8 (301.1-581.0)
343.8 (275.0-359.0)
WBC (109 cells/L)
Day 0
7.5 (5.9-9)
6.2 (5.4-7.7)
8.0 (6.8-9.1)
7.0 (6.6-7.9)
Day 1
13.0 (11.6-15.5)
16.8 (12.6-18.1)
12.2 (10.6-19.2)
11.9 (11.5-13.2)
Day 3
10.2 (8.0-12.9)
13.4 (12.4-14.5)
15.1 (12.8-21.4)
10.5 (8.3-12.5)
Day 5
10.0 (7.6-11.3)
11.8 (10.1-14.0)
11.5 (10.4-15.6)
9.3 (7.3-11.1)
Day 7
10.8 (8.6-12.5)
13.2 (11.2-16.7)
13.6 (11.7-16.9)
11.1 (9.3-12.9)
CRP (mg/L)
Day 0
3.9 (2.0-11.5)
1.0 (0.9-6.3)
3.9 (1.8-5.0)
4.0 (2.0-6.5)
Day 1
109.6 (72.1-129.2)
95.0 (87.4-102.0)
122.2 (104.6-143.8)
129.7 (102.0-154.1)
Day 3
138.9 (88.7-171.5)
118.0 (70.9-213.1)
255.5 (190.1-287.7)
221.9 (160.8-249.6)
Day 5
52.5 (38.2-86.5)
75.3 (47.8-122.0)
138.6 (86.7-193.2)
114.8 (89.5-190.0)
Day 7
40.0 (26.6-71.0)
54.3 (31.4-77.6)
81.9 (52.4-126.1)
101.9 (79.7-144.0)
AMS (μkat/L)
Day 0
N.d.
N.d.
N.d.
N.d.
Day 1
2.3 (0.7-18.8)
18.4 (7.1-53.1)
48.3 (19.9-169.0)
102.3 (39.8-186.5)
Day 3
0.8 (0.2-1.9)
9.3 (3.6-24.0)
12.0 (4.7-33.6)
3.1 (1.6-19.5)
Day 5
0.3 (0.1-0.6)
1.1 (0.8-2.7)
9.0 (2.6-26.9)
0.9 (0.3-61.4)
Day 7
0.3 (0.1-0.7)
5.2 (1.6-67.9)
14.8 (9.9-40.1)
13.5 (9.5-57.7)
WBC: white blood cell; CRP: C-reactive protein; AMS: amylase; 0: uncomplicated postoperative course; A, B, C: grades of postoperative pancreatic fistulas; N.d.: not determined; and .
