Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer

Figure 1

Increasing evidence supports the idea of a dynamic influence between host and microbiota. The fine line between human health and disease can be driven by friend (green) or foe (red) microbiota. We reported the main bacteria that could be responsible for the transition from a health to a pathological status. Commensal microorganisms are required for the maturation, education, and function of the immune system. A tight and continuous interaction of immune cells with microorganisms allows learning the difference between commensal and pathogenic bacteria that could influence immunotherapeutic treatment.