Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI

Table 1

Baseline characteristics of the total population and according to levels of dsDNA on day 1.

	All patients ()	dsDNA levels ()
		<median	>median
Age (years)	60 (53, 67)	60 (53, 68)	61 (53, 67)	0.934
Male gender	223 (82)	99 (77)	109 (89)	0.018
Current smoker	139 (51)	60 (47)	67 (55)	0.229
Body mass index (kg/m^2)	26.6 (24.4, 29.1)	26.8 (24.5, 29.2)	26.3 (24.3, 29.2)	0.701
Hypertension	73 (26.8)	35 (27)	35 (29)	0.844
Hypercholesterolemia	26 (9.6)	10 (8)	14 (11)	0.336
Diabetes mellitus	17 (6.3)	8 (6)	8 (7)	0.934
Time, symptoms to PCI (min)	185 (126, 265)	163 (113, 274)	198 (139, 265)	0.117
Anterior MI^1	131 (48.2)	54 (42)	69 (56)	0.028
Peak troponin T (ng/l)	5865 (3302, 10337)	4918 (2463, 7186)	7760 (4702, 12984)	<0.001
Peak CRP (mg/l)	19 (7, 47)	12.4 (5.7, 35.5)	30.0 (11.8, 70.2)	<0.001
HbA1c (%)	6.0 (5.7, 6.2)	6.0 (5.7, 6.2)	6.0 (5.8, 6.2)	0.233
Admission creatinine (μmol/l)	70 (62, 81)	68 (60, 80)	73 (64, 84)	0.039
Admission cholesterol (mmol/l)	5.2 (4.5, 6.0)	5.2 (4.7, 6.0)	5.0 (4.3, 6.0)	0.308

Values are presented as median values with 25th and 75th percentiles or proportions (%). ≤median: . >median: . CRP: C-reactive protein. HbA1c: glycosylated hemoglobin. MI: myocardial infarction. PCI: percutaneous coronary intervention. ¹Anterior vs. inferior or posterior MI.