A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury

<div>FC-99 alleviated LPS-induced mouse liver injury. Mice were pretreated with FC-99 (100 mg/kg, i.p. injection) 2 h prior to LPS challenge. (a, b) Serum concentrations of ALT and AST were assessed 24 h after LPS (10 mg/kg, i.p. injection) treatment. (c) Representative images of liver H&amp;E staining. Scale bar: 50 <i>μ</i>m. The histogram shows the liver injury scores based on the H&amp;E staining images. 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Mediators of Inflammation

fig5

Figure 5

Figure 5: A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury 