MiR-6803-5p Promotes Cancer Cell Proliferation and Invasion via PTPRO/NF-κB Axis in Colorectal Cancer

Figure 6

miR-6803-5p regulated cancer inflammation by targeting PTPRO. miR-6803-5p promoted mRNA expression of IL-6 and TNF-α by targeting PTPRO in HCT116 cells ( vs. control; vs. miR-6803-5p (+); ); miR-6803-5p enhanced IL-6 and TNF-α secretion of HCT116 cells via targeting PTPRO (, vs. control; vs. miR-6803-5p (+); ); miR-6803-5p elevated p-NF-κB expression by targeting PTPRO in HCT116 cells (); miR-6803-5p promoted NF-κB activation via targeting PTPRO in CRC cells ().

(a)

(b)

(c)

(d)