Research Article

Th1Th17CM Lymphocyte Subpopulation as a Predictive Biomarker of Disease Activity in Multiple Sclerosis Patients under Dimethyl Fumarate or Fingolimod Treatment

Table 2

Analysis of clinical and radiologic characteristics of the patients after 12 months of treatment.

DMF cohort ()Fingolimod cohort ()
Baseline+12 months valueBaseline+12 months value

ARR mean (SD)
 Total patients1.5 (1.01)0.14 (0.35)1.56 (1.18)0.61 (0.84)
 Naive patients1.6 (0.8)0.06 (0.26)1.72 (1.01)0.83 (0.86)
 Treated patients1.6 (1.4)0.28 (0.48)1.4 (1.35)0.46 (0.81)
Relapse-free patients (no. of patients (%))19 (86.4)25 (62.5)
Progression-free patients (no. of patients (%))21 (95)34 (85)
Free MRI activity (no. of patients (%))15 (79)25 (64)

DMF: dimethyl fumarate; ARR: annualized relapse rate.