Potential Role of Caveolin-1 in Regulating the Function of Endothelial Progenitor Cells from Experimental MODS Model

Figure 3

Cav-1 expression and EPC function during the progression of MODS. (a) The relative fold changes of EPC numbers in the control and MODS groups at indicated time points during MODS progression. (b) The relative fold changes of adhesive EPC numbers in the control and MODS groups at indicated time points during MODS progression. (c) Representative images of wound healing assay at indicated time points and its quantification at indicated time points during MODS progression. (d) Representative images of angiogenesis assay at indicated time points and its quantification at indicated time points during MODS progression. (e) The cav-1 mRNA levels in EPCs examined by RT-PCR. T1: 24 hours before operation; T2: 12 hours after resuscitation; T3: 24 hours after endotoxemia; T4: 72 hours after endotoxemia; T5: 96 hours after endotoxemia; T6: 144 hours after endotoxemia; and T7: 168 hours after endotoxemia. The data were presented as fold changes of the MODS group relative to the sham group. vs. T1.

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