Review Article
The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease
Table 3
Effects of LCFAs in the resolving phase in IBD.
| Resolving phase | The type of LCFAs | Role |
| Neutrophil trafficking | RvE1, RvD2, LXA4, and MaR1 | Inhabit PMN infiltration | Apoptosis and phagocytosis | Resolvins from n-6 and n-3 PUFAs | Promote phagocytosis of macrophages, polarize macrophages towards M2 phenotype | RvD1 | Promote phagocytosis of apoptotic macrophages | LXA4 | Promote phagocytosis of apoptotic macrophages and neutrophils | RvE1 | Promote phagocytosis of apoptotic neutrophils | Protectin D1 | Promote phagocytosis of apoptotic neutrophils |
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