IL-10 Dampens the Th1 and Tc Activation through Modulating DC Functions in BCG Vaccination
Cytokine production from DC-CD4+T cell coculture system. Spleen DCs ( cells/mL) from WT and IL-10KO BCG-vaccinated mice were cocultured with BCG-educated CD4+T cells ( cells/mL) as described in Materials and Methods. Cell supernatants were collected at 72 h for IFN γ and IL-4 detection by ELISA. Data were summarized as () and representative of three independent experiments with similar results were shown. ,.