LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis
The high expression of Cox-2 was identified in adhesion tissues and LPS induced injury in HPMCs. (a) The expression of Cox-2 in adhesive tissues of patients with adhesive intestinal obstruction. (b) The expression levels of Cox-2 in rats adhesion tissues. (c) MTT assay of cell viability in HPMCs treated with different concentration of LPS (4, 8, 12 ng/mL). (d) Flow cytometry analysis of cell apoptosis in HPMCs treated with different concentration of LPS. (e) Western blot analysis of apoptotic-associated proteins in HPMCs after different LPS treatments. (f) ELISA analysis of the expression of inflammatory factors in supernatant of HPMCs after different LPS treatments. The experiments were repeated in triplicate. Significance: and versus the controls.