Mediators of Inflammation / 2019 / Article / Fig 2

Research Article

LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB Axis

Figure 2

Effect of Cox-2 suppression on ameliorating LPS induced HPMCs injury. (a) qPCR analysis of the interference effect of sh-RNA on expression of Cox-2 in HPMCs. (b) Cox-2 suppression markedly reversed the reduced cell viability induced by LPS in HPMCs. (c) Cox-2 suppression markedly inhibited the cell apoptosis induced by LPS in HPMCs. (d) Cell apoptosis analyzed by Flow cytometry. (e) The expression of apoptosis-associated proteins after different transfections. (f) The concentration of inflammatory factors in supernatant of HPMCs after different transfections. The experiments were repeated in triplicate. Significance: and versus the controls.

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