Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection

Table 5

Association between cytokines, clinical characteristics, and the presence of AAD was assessed by univariate analysis and multivariate linear regression analysis.

Variables	Simple linear			Multiple linear
	Beta	95% CI	value	Beta	95% CI	value
IL-18	0.509	0.351 to 0.667	0.001	0.238	0.053 to 0.422	0.012
IFN-γ	0.522	0.366 to 0.678	0.001	0.232	0.044 to 0.419	0.016
IL-6	0.419	0.252 to 0.585	0.001	0.163	0.002 to 0.324	0.048
Gender	0.185	0.005 to 0.364	0.045	0.124	-0.029 to 0.276	0.111
Smoking	0.198	0.018 to 0.377	0.031	0.137	-0.014 to 0.288	0.075
Glu	0.345	0.173 to 0.517	0.001	0.045	-0.116 to 0.205	0.583
CREA	0.216	0.037 to 0.395	0.018	-0.024	-0.176 to 0.128	0.754
D-dimer	0.464	0.302 to 0.626	0.001	0.179	0.014 to 0.343	0.034
SBP	-0.149	-0.330 to 0.032	0.107
DBP	-0.102	-0.284 to 0.080	0.269
TG	-0.068	-0.250 to 0.115	0.465
TC	0.034	-0.149 to 0.217	0.716
CRP	-0.028	-0.211 to 0.155	0.760
WBC	0.140	-0.041 to 0.322	0.128
Age	-0.130	-0.312 to 0.052	0.159
HR	0.170	-0.011 to 0.350	0.065