Review Article

Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the Course and Prognosis of Inflammatory Conditions

Table 2

Decreased MPV in various diseases [15, 20, 22, 24, 2736].

MPV in tuberculosis
Gunluoglu et al. 2014 [27]During disease exacerbation can be related to the formation of microthrombi in tuberculous cavities
MPV in ulcerative colitis
Yuksel et al. 2009 [28]Associated with increased activity of ulcerative colitis
MPV in rheumatoid diseases
Gasparyan et al. 2010 [15]In rheumatoid arthritis associated with disease exacerbation
Delgado-Garcia et al. 2016 [29]In adult patients can be related to active SLE
MPV in carcinomas
Li et al. 2017 [20]An independent prognostic factor of patients’ survival after intestinal tumor resection
Inanc et al. 2014 [30]In colorectal cancer patients effect of chemotherapy (XELOX and XELOX-bevacizumab)
Shen et al. 2016 [31]Prior to therapy is a good prognostic factor of survival and recovery after gastric tumor resection
Kılınçalp et al. 2014 [22]In primary gastric cancer patients significant reduction after surgery
Karaman et al. 2011 [32]A useful marker in differentiation patients with neuroendocrine tumor of the pancreas from pancreatic adenocarcinoma
Gong et al. 2016 [24]In pancreatic cancer patients significant reduction after surgery
Yun et al. 2017 [33]In renal cell carcinoma patients may be a result of (1) inflammation which probably lead to excessive platelet consumption and/or (2) platelet involvement in angiogenesis, migration, and invasion of cancer cells
Inagaki et al. 2014 [34]In patients with non-small-cell lung cancer resulted from inverse nonlinear correlation between platelet count and their volume
Kumagai et al. 2015 [35]In lung cancer, low preoperative level is an independent unfavorable prognostic factor in patients after total cancer resection
Shen et al. 2017 [36]Independently related to the presence of cancer of the uterine cervix