Immune Mediator Profile in Aqueous Humor Differs in Patients with Primary Acquired Ocular Toxoplasmosis and Recurrent Acute Ocular Toxoplasmosis
Table 1
Clinical characteristics of the patient in the primary and recurrent OT groups and control group.
Primary OT
Recurrent OT
Control group
value
Number of patients ()
21/62 (33.9%)
30/62 (48.4%)
11/62 (17.7%)
Gender
Male: 42.9% (9/21)
Male: 36.6% (11/30)
Male: 63.6% (7/11)
Interval between consultation and aqueous humor sampling (days)
Observation time after aqueous humor sampling (days)
Mean age at first episode ()
Mean age at aqueous humor sampling ()
pOT/rOT vs control: , pOT vs rOT:
years: 18 patients
years: 12 patients
Median grading of inflammation in vitreous humor (grade 0-4, min.-max.)
1 (1-3)
0.8 (0.8-2)
Median grading of inflammation in the anterior chamber (grade 0-4, min.-max.)
0 (0-2)
0 (0-3)
Median number of active lesions (, min.-max.)
1 (1-1)
1 (1-4)
Median size of active lesions (PD, min.-max.)
1 (0-3)
0.3 (0-8)
Median number of scars (, min.-max.)
0
1 (1-7)
Bilateral OT involvement
0
20% (6/30)
Median number of recurrent active episodes (n)
∅
1.5 (1-18)
years: 2 recurrences
years: 1 recurrence
Macular involvement
9.5% (2/21)
13.3% (4/30)
Risk of recurrences
years: 2.34 times higher than >40 years
A summary of the patients’ demographics and clinical characteristics in the primary and recurrent OT groups and control group. OT: ocular toxoplasmosis; SD: standard deviation; PD: diameter of the papilla; value < 0.05 is considered as statistically significant; significant values are shown in bold.