Table 2: Chemokine, growth factor, angiogenetic factor, and wound healing factor concentration in aqueous humor of a control group and patients with pOT and rOT ().

Immune mediatorMdn concentration in patients with pOT, (IQR) (pg/ml)Mdn concentration in patients with rOT, (IQR) (pg/ml)Mdn concentration in patients in the control group, (IQR) (pg/ml)pOT vs control valuerOT vs control valuepOT vs rOT value

T cell development-promoting cytokine
IL-2183 (0, 315)123 (0, 233)0 (0, 0)<0.0010.0030.324
Th1-cytokines
IFN-γ760 (218, 2.93103)348 (62.7, 909)0 (0, 0)<0.0001<0.0010.129
TNF-α55.2 (15.6, 111.4)22.6 (4.53, 64.9)0 (0, 0)<0.00001<0.0010.104
Th1 cell development-promoting cytokines
IL-12p70233 (114, 423)132 (81.2, 289)192 (158, 384)0.7610.2050.241
IL-7654 (464, 1.19103)450 (318, 937)772 (532, 851)0.9160.0970.028
IL-1579.8 (39.9, 217)47.5 (12.5, 136.5)0 (0, 23.4)<0.00010.0040.084
Th2 cytokines
IL-429.4 (4.48, 59.6)16.2 (0, 38.6)0 (0, 0)<0.0001<0.0010.183
IL-549.2 (22.8, 149)37.1 (15.5, 93.6)0 (0, 0)<0.0001<0.0010.380
IL-9135 (58.7, 345)93.5 (14.9, 205)0 (0, 0.62)<0.000010.0010.054
IL-1067.9 (2.43, 176)19.8 (0, 102)1.99 (1.59, 49.8)0.1060.5210.188
IL-13345.4 (204, 1.05103)194 (77.9, 647)230 (103, 286)0.0220.4020.051
Th17 cytokines
IL-1779.9 (0, 371)0 (0, 234)0 (0, 0)0.0010.0140.237
IL-1Rα262 (53.5, 648)130 (0, 337)0 (0, 0)<0.00010.0020.207
Th17 cell development-promoting cytokines
IL-62.74103 (738, 6.01103)1.06103 (173, 3.99103)150 (1.54, 409)<0.00010.0040.108
IL-1β3.96 (0.57, 8.11)1.38 (0, 5.36)0 (0, 1.49)0.0030.0320.220

pOT: primary OT; rOT: recurrent OT: Mdn: median; IQR: interquartile range; significant values are shown in bold; italic values are below LLOQ as defined by the manufacturer.