Table 3: Chemokines, growth factor, angiogenetic factor, and wound healing factor concentrations in aqueous humor of a control group and patients with pOT and rOT ().

Immune mediatorMdn concentration in patients with pOT, (IQR) (pg/ml)Mdn concentration in patients with rOT, (IQR) (pg/ml)Mdn concentration in patients in the control group, (IQR) (pg/ml)pOT vs control valuerOT vs control valuepOT vs rOT value

Chemokines
MIP-1α271 (134, 412)157 (56.7, 451)0 (0, 41.2)<0.0001<0.0010.331
MIP-1β396 (299, 604)283 (178, 593)218 (166, 341)0.0230.2100.153
IP-105.97105 (7.93104, 9.38105)1.52105 (2.75104, 7.99105)5.75103 (3.17103, 13.0104)<0.00001<0.00010.235
Eotaxin925 (241, 1.32103)755 (0, 1.01103)1.95 (0, 290)<0.0010.0070.302
IL-8280 (128, 937)120 (51.6, 611)56.5 (0, 90.2)<0.0010.0090.166
RANTES219 (61.3, 296)91.1 (7.4, 372)0 (0, 0)<0.0001<0.0010.366
PDGF-bb288 (63.8, 598)164 (0, 419)0 (0, 0)<0.0010.0010.378
Growth, angiogenetic, and wound healing factors
GM-CSF0 (0, 169)0 (0, 98.7)0 (0, 0)0.0360.0670.639
G-CSF513 (68.8, 1.76103)195 (5.37, 999)0 (0, 435)0.0040.0340.258
MCP-12.13103 (1.14103, 5.45103)1.48103 (1.05103, 2.41103)958 (667, 1.34103)<0.0010.0090.151
VEGF1.13103 (394, 1.78103)908 (246, 1.85103)1.29103 (828, 1.68103)0.7460.4690.637
FGF basic38.2 (2.87, 80.6)27.6 (0.67, 60.4)0 (0, 57.5)0.0660.2450.333

pOT: primary OT; rOT: recurrent OT, Mdn: median, IQR: interquartile range: significant values are shown in bold; italic values are below LLOQ as defined by the manufacturer.