Research Article

IL-37 Plays a Beneficial Role in Patients with Acute Coronary Syndrome

Figure 2

IL-37 significantly upregulated the frequencies of Tregs in the UA group and the AMI group compared with PBS-treated activated PBMCs. PBMCs were activated by anti-CD3 and anti-CD28 antibodies for 24 h in the presence or absence of 30 ng/mL IL-37. (a) Representative images of Tregs (CD4+Foxp3+/CD4+ T cells) are shown. (b) Results of statistical analysis of average percentages of Tregs. All data are expressed as , and differences were evaluated using Student -test. NCA (), SA (), UA (), and AMI (). indicates . ns: not significant; NCA: normal coronary artery; SA: stable angina; UA: unstable angina; AMI: acute myocardial infarction.
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