IL18 Polymorphism and Periodontitis Susceptibility, Regardless of IL12B, MMP9, and Smoking Habits

Table 3

IL18 genotype frequency distributions between nonsmoker CP and controls considering the interaction analysis with the covariant gender.

	CP patients; (%)	Controls; (%)			OR (95% CI)
IL18-137G/G (rs187238)
Female	22 (48)	51 (68)	ref
Male	26 (52)	24 (32)	0.01	0.03	2.51 (1.19-5.30)
IL18-607C/C (rs1946518)
Female	14 (45)	38 (73)	ref
Male	17 (55)	14 (27)	0.01	0.03	3.30 (1.29-8.40)

: number; ref: reference; : value; OR: odds ratio; CI: confidence interval; CP: chronic periodontitis.