Research Article

The lncRNA SOX2OT rs9839776 C>T Polymorphism Indicates Recurrent Miscarriage Susceptibility in a Southern Chinese Population

Table 2

Genotype and allele frequencies of SOX2OT in RM patients and controls.

Genotype/alleleRM ()Controls () valueaOR (95% CI) valueAdjusted OR (95% CI) valueb

SOX2OT/rs9839776 C>T ()
CC361 (63.33)369 (63.84)1.00/1.00/
CT182 (31.93)180 (31.14)/1.351 (1.061-1.721)0.01461.357 (1.065-1.728)0.0134
TT27 (4.74)29 (5.02)/1.244 (0.726-2.133)0.42681.247 (0.727-2.139)0.422
Additive0.94441.007 (0.826-1.228)0.94741.007 (0.826-1.228)0.9439
Dominant209 (36.67)209 (36.16)0.85821.022 (0.804-1.300)0.85821.024 (0.805-1.303)0.8451
Recessive543 (95.26)549 (94.98)0.82540.941 (0.550-1.611)0.82550.935 (0.546-1.601)0.8061

a test for genotype distributions between recurrent miscarriage patients and controls. bAdjusted for age. RM: recurrent miscarriage.