Research Article
Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose
Figure 3
PTX3 is related to eNOS in vitro. (a) With the addition of TPCA-1, expression of PTX3 and p-eNOS/eNOS protein improved and was dose-dependent. (b) siRNA interference can effectively silence the expression of PTX3 in HUVECs (immunofluorescence showed Cy3 labeling control group and real-time PCR). (c) After PTX3 was silenced by siRNA, the expression of p-eNOS/eNOS protein was significantly higher than that in the HG group. con: control; HG: high glucose; compared with the control group, ; #compared with the HG group, ).
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