Clinical Differences between Eosinophilic and Noneosinophilic Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study

Table 2

Clinical features and laboratory data of the patients with AECOPD ().

	NEOS-AECOPD ()	MEOS-AECOPD ()	SEOS-AECOPD ()	Statistical values
Fever	29	0	7	18.622	0.000
WBCs (×10^9/L)				19.396	0.000
NS (×10^9/L)				17.341	0.000
Lymphocytes (×10^9/L)				1.253	0.287
EOS (×10^9/L)				71.795	0.000
NS%				11.008	0.000
Lymphocyte%				19.520	0.000
EOS%				170.959	0.000
NLR				19.620	0.000
RBCs (×10^12/L)				1.474	0.230
Hb (g/L)				0.944	0.390
Hct (%)				1.337	0.264
PLTs (×10^9/L)				1.301	0.273
PCT (ng/mL)				3.545	0.030
CRP (mg/mL)				4.563	0.011
ESR (mm/first hour)				3.095	0.046
ABG
pH				0.458	0.633
PaCO2 (mmHg)				1.600	0.203
PaO2 (mmHg)				1.115	0.329
Oxygen index (OI)				0.075	0.928
AB (mmol/L)				2.582	0.077
SB (mmol/L)				2.505	0.083
AG				14.966	0.000
Serum Na^+ (mmol/L)				4.308	0.014
Serum K^+ (mmol/L)				3.737	0.025
Serum Ca^2+ (mmol/L)				3.452	0.033
Serum Mg^2+ (mmol/L)				6.539	0.002
ALB (g/L)				2.703	0.068
BUN (mmol/L)				4.539	0.011
Cr (μmol/L)				0.196	0.822
ALT (U/L)				0.836	0.434
AST (U/L)				1.030	0.358
IBIL (μmol/L)				1.826	0.162
DBIL (μmol/L)				8.000	0.000
RBG (mmol/L)				1.136	0.322
LHS (days)				4.233	0.015
MV				8.671	0.013
Nonventilation	187	59	170
NIPPV	26	4	8
IPPV	1	0	0

Abbreviations: WBCs: white blood cells; NS: neutrophils; EOS: eosinophils; NLR: neutrophil-to-lymphocyte ratio; RBCs: red blood cells; PLTs: platelets; Hb: hemoglobin; Hct: hematocrit; PCT: procalcitonin; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; ABG: air blood gas; AB: actual base; SB: standard base; AG: anion gap; Na⁺: sodium; K⁺: potassium; Ca²⁺: calcium; Mg²⁺: magnesium; ALB: albumin; Cr: creatinine; BUN: blood urea nitrogen; ALT: alanine aminotransferase; AST: aspartate aminotransferase; IBIL: indirect bilirubin; DBIL: direct bilirubin; RBG: random blood glucose; LHS: length of hospital stay; MV: mechanical ventilation; NIPPV: noninvasive positive pressure ventilation; IPPV: invasive positive pressure ventilation.